Stimulation mécanique (compression)

Technical Feasibility of an Ex Vivo Bovine Trabecular Bone-Titanium Implant Co-Culture Platform for Early Interface Studies

Coralie Nagels; Bianca Riedel; Sunil Shetty; Hagen Schmal; Martin P. Pichotka; Ralf Thomann; Michael Seidenstuecker

Journal of Functional Biomaterials. 2026;17(11):538. Published 23 October 2026.

0 citations · 0 en 2025–2026

Growth- and Sex-Dependent Changes in Bone, Bone Marrow Adipose Tissue, and the Lipid Microenvironment in Healthy C57BL/6 Mice

Alana Ruth Stahl

University of Calgary, Open Theses and Dissertations, Published: 2026-09-02

0 citations · 0 en 2025–2026

The effect of perfusion with and without mechanical loading on an in vitro model of the outer annulus fibrosus-cartilage endplate interface

Campbell Thom; J․Paul Santerre; Rita A. Kandel

Acta Biomaterialia, Volume 215, 2026, Pages 181-194, ISSN 1742-7061, Published: May 2026

2 citations · 2 en 2025–2026

Biofunctional coatings for 3D-printed bone scaffolds: A comparative study on polydopamine-assisted bioactive ceramic coatings

MinJoo Kim; Qaisar Nawaz; Bastian Hartmann; Pedro Henrique da Rosa Braun; Constanze Eulenkamp; Jan Torgersen; Hauke Clausen-Schaumann; Aldo Roberto Boccaccini; Boris Michael Holzapfel; Susanne Mayer-Wagner

Chemical Engineering Journal, Volume 533, 2026, 174600, ISSN 1385-8947, Published: 1 April 2026

4 citations · 4 en 2025–2026

Highly tunable chitosan and carboxymethylated dextran hydrogels crosslinked with NHS/EDC with potential application for preventing postoperative adhesions

Vaiana Moreau; Benoît Liberelle; Faranak Baniahmad; Nick Virgilio; Gregory De Crescenzo

Carbohydrate Polymer Technologies and Applications, Volume 13, 2026, 101101, ISSN 2666-8939, Published: March 2026

0 citations · 0 en 2025–2026

Integrin inhibition facilitates fibrocartilaginous transformation in connective tissue in osteoarthritis

Ruiye Bi; Xianni Yang; Haohan Li; Yanjing Zhan; Qing Yin; Han Fang; Ziqian Wang; Binbin Ying; Haopeng Yu; Songsong Zhu

Science Advances, Vol 12, Issue 1, Published: 2 Jan 2026

4 citations · 4 en 2025–2026

The Role of Viscoelasticity in a Biomimetic Hyaluronan-Oxime Hydrogel Modelling Heterogeneous Glioblastoma Stem Cell Invasion

Nicole Juliane Blaine

University of Toronto, School of Graduate Studies, Master's Theses, Published: October 2025

0 citations · 0 en 2025–2026

Vocal Fold Scar Treatment via Controlled Dexamethasone Delivery With a Light-Activatable Implant

Denzel Ryan D. Cruz; Nour Awad; Avery Zheng; Alexander Karabachev; Charles Farbos de Luzan; Yoonjee C. Park; Gregory R. Dion

Epub ahead of print. PMID: 40964826; PMCID: PMC12581502, Published: 2025 Sep 18

3 citations · 3 en 2025–2026

An in silico approach to the mechanical design of meta-materials for adipose tissue engineering

Emanuele Luigi Carniel; Chiara Giulia Fontanella; Maria Vittoria Mascolini; Sofia Pettenuzzo; Ilaria Toniolo; Alice Berardo

Research article, Volume 11, Issue 10e43430, Published: May 2025

2 citations · 2 en 2025–2026

Targeted immunotherapy rescues pulmonary fibrosis by reducing activated fibroblasts and regulating alveolar cell profile

Jing Yan; Song-Yu Wang; Qi Su; Min-Wen Zou; Zi-Yue Zhou; Jian Shou; Yunlong Huo

Nat Commun 16, 3748 (2025), Published: 21 April 2025

63 citations · 63 en 2025–2026

Electromagnetic interference shielding in soft, lightweight, and flexible conducting polymer-based sponges

Biporjoy Sarkar; Floriane Miquet-Westphal; Jiaxin Fan; Gayaneh Petrossian; Fabio Cicoira

IOP Publishing Ltd, Biporjoy Sarkar et al 2025 Flex. Print. Electron. 10 025002, Published: 3 April 2025

2 citations · 2 en 2025–2026

Mechanical characterization of an origami-inspired super deformable metamaterial with high tunability for tissue engineering

M.A. Bagheri; C.E. Aubin; M.L. Nault; I. Villemure

Materials & Design, Volume 251, 2025, 113701, ISSN 0264-1275, Published: March 2025

10 citations · 10 en 2025–2026

Trabecular Bone Adaptation: An Experimental and Computational Investigation

Mahsa Zojaji

Queen’s University, PhD, March 2025 (cover); repository deposit 24 March 2025 not asserted as defence date. Original complete English abstract from repository, checked against thesis. Original bovine methods: Chapter 3 PDF pp.51–52 and Chapter 5 pp.107–110. Bovine detail is tied to these verified experiments; the abstract also describes human computational models, not used here to infer human Mach-1 testing. Bioreactor does not alone prove a confined compression configuration. Chapters and related papers are not additional independent experiments.

Development of Reliable and High - Throughput Human Biomimetic Cartilage and Bone Models to Explore Senescence and Personalized Osteoarthritis Treatment Options

Ilja Boone; Evelyn Houtman; Margo Tuerlings; Jim J. van den Berg; Johannes Lehmann; Peter L. J. de Keizer; Rob G. H. H. Nelissen; Ingrid Meulenbelt

J Orthop Res. 2025, PMID: 39960283; PMCID: PMC11982592, Published: 17Feb2025

8 citations · 8 en 2025–2026

Design and characterization of an optical phantom for mesoscopic multimodal fluorescence lifetime imaging and optical coherence elastography

Luis Chavez; Shan Gao; Vikas Pandey; Nanxue Yuan; Saif Ragab; Jiayue Li; Matt S. Hepburn; Percy Smith; Caroline Edelheit; David T. Corr; Brendan F. Kennedy; Xavier Intes

Biomedical Optics Express Vol. 16, Issue 3, pp. 1006-1024 (2025), Published: February 12, 2025

3 citations · 2 en 2025–2026

Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation

Jiawei Huang; Qingwen Deng; Lai Ling Tsang; Guozhu Chang; Jinghui Guo; Ye Chun Ruan; Chi Chiu Wang; Gang Li; Hon Fai Chan; Xiaohu Zhang; Xiaohua Jiang

Stem Cell Res Ther 16, 59 (2025), Published: 08 February 2025

39 citations · 39 en 2025–2026

Improvement and Evaluation of a 3D Printable Bioreactor Chamber for Ex Vivo Trabecular Bovine Bone Core Testing with Mechanical Stimulation

ALEJANDRA VICTORIA CORREA BELLOSO

Thesis, 2024. Repository: https://repositorio.uai.cl/handle/20.500.12858/6892

A damaging COL6A3 variant alters the MIR31HG-regulated response of chondrocytes in neocartilage organoids to hyperphysiologic mechanical loading

Niek GC Bloks; Zainab Harissa; Giorgia Mazzini; Shaunak S Adkar; Amanda R Dicks; Ghazaleh Hajmousa; Nancy Steward; Roman I. Koning; Aat Mulder; Berend B.R. de Koning; Margreet Kloppenburg; Rodrigo Coutinho de Almeida; Yolande FM Ramos; Farshid Guilak; Ingrid Meulenbelt

Adv. Sci. 2024, 11, 2400720, First published: 17 July 2024

18 citations · 18 en 2025–2026

Age and Gender Related Variability in the Strength of Auricular Cartilage in Living Humans

Fuat Buyuklu; Mert Poyraz Cakmak; Berk Ayaz Cakmak; Elif Durukan; Evren Hizal

Aesth Plast Surg (2024)., Published: 18 November 2024

3 citations · 3 en 2025–2026

Dithiolane-ene Photopolymerization of Covalent and Supramolecular Networks Permits Cyclic Compressive Loading in 3D Cell Culture

Ying Chen; Ciqing Tong; Merel L. Janssen; Isabel Sariol; Joeri A. J. Wondergem; Marijn van den Brink; Rob G. H. H. Nelissen; Doris Heinrich; Yolande F. M. Ramos; Roxanne E. Kieltyka

Research manuscript reproduced as Chapter 3, pp.65–111, in Ying Chen, Squaramide-based interpenetrated networks for load-bearing applications. Doctoral thesis, Leiden University,2024. This is the 2024 thesis manuscript, not the separately titled 2026 journal article; no manuscript DOI established.

Mechanical loading of ex vivo bovine trabecular bone in 3D printed bioreactor chambers

Brian A. Kunath; Kail Beloglowka; Roshni Rainbow; Heidi-Lynn Ploeg

Journal of the Mechanical Behavior of Biomedical Materials 153 (2024), 106470. Original abstract: English.

5 citations · 4 en 2025–2026

Mechanical stress and inflammation have opposite effects on Wnt signaling in human chondrocytes

Ritchie G. M. Timmermans; Arjen B. Blom; Rob G. H. H. Nelissen; Demiën Broekhuis; Peter M. van der Kraan; Ingrid Meulenbelt; Martijn H. J. van den Bosch; Yolande F. M. Ramos

Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2024;42(2):286-295.

4 citations · 2 en 2025–2026

Optical Measurement of Directional, Regional, and Strain Rate Dependent Mechanical Properties of Human Brain Tissue under Uniaxial Compression

Alejandro Matos Camarillo

University of Alberta, A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science, Graduation date: Spring 2024

Photon-counting in dual-contrast-enhanced computed tomography: a proof-of-concept quantitative biomechanical assessment of articular cartilage

Petri Paakkari; Satu I. Inkinen; Ali Mohammadi; Miika T. Nieminen; Anisha Joenathan; Mark W. Grinstaff; Juha Töyräs; Janne T. A. Mäkelä; Juuso T. J. Honkanen

Scientific Reports volume 14, Article number: 29956 (2024) Published: 02 December 2024

2 citations · 2 en 2025–2026

T-Cell Differentiation from Hematopoietic Progenitor Cells Using 3D Thymic-like Hydrogels

Asel Primbetova; Han Hsuan Hsu; Alexander Baker; Ross Jones; Carla Zimmerman; Molly Shoichet; Peter W. Zandstra

GEN Biotechnology, Vol. 3, No. 3, Published Online: 22 June 2024

4 citations · 4 en 2025–2026

The role of mitochondrial reactive oxygen species in chondrocyte mechanotransduction

Aisha Momin; Simona Perrotti; Stephen D. Waldman

Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2024;42(3):628-637.

10 citations · 8 en 2025–2026

Mechanical Loading of Ex Vivo Bovine Trabecular Bone in 3D-Printed Bioreactors

Alejandra V. Correa; Mahsa Zojaji; Andrew Parkhill; Brian A. Kunath; Juan F. Vivanco; Roshni Rainbow; Heidi-Lynn Ploeg

28th Congress of the European Society of Biomechanics, 9–12 July 2023, Maastricht. Original structured meeting abstract: English.

5 citations · 4 en 2025–2026

Mechanical manipulation of cancer cell tumorigenicity via heat shock protein signaling

Siu Hong Dexter Wong; Bohan Yin; Zhuo Li; Weihao Yuan; Qin Zhang; Xian Xie; Youhua Tan; Nathalie Wong; Kunyu Zhang; Liming Bian

SCIENCE ADVANCES, VOL. 9, NO. 27, Published: 07Jul2023

43 citations · 31 en 2025–2026

Ex Vivo Mechanical Testing and FEA Modelling of Bovine Trabecular Bone

Kail Beloglowka

Queen’s University, MASc, September 2022 (cover). Original complete English abstract from official repository, checked against PDF p.2; stray export character after Eapp removed, no words rewritten. Methods 3.3.3 and 4.3, PDF pp.36–38 and 47, confirm direct Mach-1 quasi-static compression and cyclic stimulation of bovine trabecular bone. Lateral confinement not assumed from the bioreactor. Shared co-authorship and bone-culture data with Kunath are documented in thesis co-authorship statement; the theses are distinct documents, not independent replicate experiments.

Design and Validation of an Open-Source 3D Printable Bioreactor System for Ex Vivo Bone Culture

Brian A. Kunath

Queen’s University, MASc, June 2022 (cover). Original complete English abstract from repository, checked against thesis. Methods 3.4.3.4 and 5.3.4, PDF pp.48–49 and 73–74, confirm direct Mach-1 compression and stimulation, not fixture-only use. Lateral confinement is not inferred merely from a chamber. Appendix C calibration is recorded separately; MED610 biocompatibility and published related article are not additional Mach-1 material experiments.

Lithium chloride-induced primary cilia recovery enhances biosynthetic response of chondrocytes to mechanical stimulation

Arianna Soave; Loraine L. Y. Chiu; Aisha Momin; Stephen D. Waldman

Biomechanics and Modeling in Mechanobiology. 2022;21(2):605-614. DOI:10.1007/s10237-021-01551-4. First online 2022-01-29. Methods provenance:Soave2021thesis;quantitative same-study correspondence verified. Not an explicit reprint;final journal methods not independently read.

9 citations · 4 en 2025–2026

Inhibiting thyroid activation in aged human explants prevents mechanical induced detrimental signalling by mitigating metabolic processes

Evelyn Houtman; Margo Tuerlings; H Eka D Suchiman; Nico Lakenberg; Frederique M F Cornelis; Hailiang Mei; Demiën Broekhuis; Rob G H H Nelissen; Rodrigo Coutinho de Almeida; Yolande F M Ramos; Rik J Lories; Luis J Cruz; Ingrid Meulenbelt

Rheumatology (Oxford, England). 2022;62(1):457-466.

7 citations · 2 en 2025–2026

Characterization of dynamic changes in Matrix Gla Protein (MGP) gene expression as function of genetic risk alleles, osteoarthritis relevant stimuli, and the vitamin K inhibitor warfarin

E. Houtman; R. Coutinho de Almeida; M. Tuerlings; H.E.D. Suchiman; D. Broekhuis; R.G.H.H. Nelissen; Y.F.M. Ramos; J.B.J. van Meurs; I. Meulenbelt

Osteoarthritis and Cartilage. 2021;29(8):1193–1202.

17 citations · 3 en 2025–2026

Effects of Lithium Chloride on Chondrocyte Primary Cilia in 3D Culture

Arianna Soave

Ryerson University. MASc thesis, 2021. Cover year: 2021; Scholar export: 2023. Original abstract: English.

1 citation · 0 en 2025–2026

Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis

Evelyn Houtman; Marcella van Hoolwerff; Nico Lakenberg; Eka H. D. Suchiman; Enrike van der Linden-van der Zwaag; Rob G. H. H. Nelissen; Yolande F. M. Ramos; Ingrid Meulenbelt

Rheumatol Ther (2021). https://doi.org/10.1007/s40744-021-00287-y

25 citations · 11 en 2025–2026

The Role of Mitochondrial Reactive Oxygen Species in Chondrocyte Mechanotransduction

Aisha Momin

MASc thesis, Ryerson University, 2021 (title-page degree/copyright year). Repository deposited 18 December 2023. Distinct from the 2024 journal article 10.1002/jor.25709.

0 citations · 0 en 2025–2026

High Throughput Screening of Cell Mechanical Response Using a Stretchable 3D Cellular Microarray Platform

Kabilan Sakthivel; Hitendra Kumar; Mohamed G. A. Mohamed; Bahram Talebjedi; Justin Shim; Homayoun Najjaran; Mina Hoorfar; Keekyoung Kim

Small 2020, 2000941. https://doi.org/10.1002/smll.202000941

27 citations · 7 en 2025–2026

Isolated Cyclic Loading during Adolescence Improves Tibial Bone Microstructure and Strength at Adulthood

Tanvir Mustafy; Irène Londono; Florina Moldovan; Isabelle Villemure

ASBMR doi: 10.1002/jbm4.10349

7 citations · 1 en 2025–2026

Mechanical and Glucose Stimulation of Bovine Chondrocytes Affect ECM Synthesis

Christian Lecce

Ryerson University. MEng major research project, 2020. Repository/Scholar date 2023 differs from cover year and repository Year field. The introductory protocol differs from Methods; the equipment note follows the explicit Methods section. Original abstract: English.

0 citations · 0 en 2025–2026

Development of an In Vitro Outer Annulus Fibrosus Cartilage Endplate Model and its Response to Dynamic Mechanical Loading

J. E. Chong

Université de Toronto

Experimental and finite element analyses of bone strains in the growing rat tibia induced by in vivo axial compression

Tanvir Mustafy; Irène Londono; Isabelle Villemure

Journal of the Mechanical Behavior of Biomedical Materials

13 citations · 4 en 2025–2026

High Impact Exercise Improves Bone Microstructure and Strength in Growing Rats

Tanvir Mustafy; Irène Londono; Florina Moldovan; Isabelle Villemure

Nature Scientific Reports, volume 9, Article number: 13128 (2019) https://doi.org/10.1038/s41598-019-49432-2

36 citations · 11 en 2025–2026

Recovery of Passaged Cells Through the Recapitulation of the Pericellular Matrix

Stefan Balko

Thesis, 2019. Repository: https://ndownloader.figshare.com/files/28129857

The Short and Long Term Effects of in Vivo Cyclic Axial Compression Applied During Puberty on Bone Growth, Morphometry and Biomechanics

Tanvir Mustafy

Polytechnique Montréal. PhD. 2019

1 citation · 0 en 2025–2026

Promoting intracellular delivery of sub-25 nm nanoparticles via defined levels of compression

Hongrong Yang; Yifei Yao; Huize Li; Lok Wai Cola Ho; Bohan Yin; Wing-Yin Yung; Ken Cham-Fai Leung; Arthur Fuk-Tat Mak; Chung Hang Jonathan Choi

Nanoscale.2018;10(31):15090–15102. Firstonline24July2018;issue21August2018. DOI10.1039/c8nr04927k.

16 citations · 3 en 2025–2026

Addition of excess thyroid hormone induces detrimental changes in human ex vivo full thickness osteochondral explants

E. Houtman; M. van Hoolwerff; A. Rodríguez Ruiz; N. Lakenberg; E. Suchiman; R. Nelissen; Y. Ramos; I. Meulenbelt

Osteoarthritis and Cartilage 26 (2018) S400 https://doi.org/10.1016/j.joca.2018.02.777

3 citations · 0 en 2025–2026

Stochastic Resonance with Dynamic Compression Improves the Growth of Adult Chondrocytes in Agarose Gel Constructs

Joanna F. Weber; Loraine L.Y. Chiu; Stefan Balko; Stephen D. Waldman

Weber, J.F., Chiu, L.L., Balko, S. et al. Ann Biomed Eng (2018). https://doi.org/10.1007/s10439-018-02123-x

17 citations · 3 en 2025–2026

Cellularized collagen gels for tissue engineered vascular wall: in vitro models alternative to in vivo testing

Loy Caroline; Meghezi S�bastien; Seifu Dawit; Pezzoli Daniele; Bono Nina; Levesque Lucie; Drouin Bernard; Mantovani Diego

Poster #P.0616 on Thursday May 19 from 15:00 to 16:30 in room 220BCD (P3) during World Biomaterials Congress, Montreal, May 2016.

0 citations · 0 en 2025–2026

Change in viability of C2C12 myoblasts under compression, shear and oxidative challenges

Ye Hong; Yifei Yao; Singwan Wong; Liming Bian; Arthur F.T. Mak

Journal of biomechanics, 49(8), 1305-1310. (2016)

12 citations · 2 en 2025–2026

Effects of Biowastes Released by Mechanically Damaged Muscle Cells on the Propagation of Deep Tissue Injury: A Multiphysics Study

Yifei Yao; Lucas Xian Da Ong; Xiaotong Li; Kinlun Wan; Arthur F. T. Mak

Annals of Biomedical Engineering March 2017, Volume 45, Issue 3, pp 761–774

5 citations · 0 en 2025–2026

Strengthening of C2C12 mouse myoblasts against compression damage by mild cyclic compressive stimulation

Yifei Yao; Arthur FT. Mak

J Biomech. 2016 Dec 8;49(16):3956-3961. doi: 10.1016/j.jbiomech.2016.11.050. Epub 2016 Nov 16

5 citations · 3 en 2025–2026

Dynamic Axial Loading Disrupts Lateral Integration of Arthritic Human Articular Cartilage and Synthetic Tissue Engineered Scaffolds in an Ex Vivo Ring Model

Mintz BR; Papaliodis D; Jordan S; Leonard G; Mulligan M; Cooper JA

Orthopeadic Research Society Annual Meeting in Las Vegas, 2015, Abstract 0390

Stochastic resonance is a method to improve the biosynthetic response of chondrocytes to mechanical stimulation

Joanna F. Weber; Stephen D. Waldman

Journal of Orthopaedic Research 08/2015; DOI:10.1002/jor.23000

25 citations · 0 en 2025–2026

The Effect Of Superimposed Vibrations On Chondrocytes Subjected To Dynamic Compressive Loading

Weber J; Waldman S

Orthopeadic Research Society Annual Meeting in Las Vegas, Abstract 1244

The Effects of Oxidative Stress on the Compressive Damage Thresholds of C2C12 Mouse Myoblasts: Implications for Deep Tissue Injury

Yifei Yao; Zhitao Xiao; Singwan Wong; Yu-Chun Hsu; Truman Cheng; Chih-Chieh Chang; Liming Bian; Arthur F. T. Mak

Ann Biomed Eng. 2015 Feb;43(2):287-96. doi: 10.1007/s10439-014-1239-6. Epub 2015 Jan 6.

17 citations · 3 en 2025–2026

The sensitivity of articular chondrocytes to dynamic mechanical stimulation

Joanna Frances Weber

PhD thesis, Queen’s University, December 2015. Repository deposit/index year: 2016.

7 citations · 0 en 2025–2026

The effect of terminal sterilization on structural and biophysical properties of a decellularized collagen-based scaffold; implications for stem cell adhesion

Andrea M. Matuska; Peter S. McFetridge

J Biomed Mater Res Part B, 2014, pp 1-10

119 citations · 15 en 2025–2026

Simulated joint loading enhances the expression of superficial zone markers in tissue engineered cartilage constructs

James Arthur Kaupp

Thesis, Queen’s University, 2012.

0 citations · 0 en 2025–2026

Growth plate explants respond differently to in vitro static and dynamic loadings

Kim Sergerie; Stefan Parent; Pierre‐Francois Beauchemin; Irene Londoño; Florina Moldovan; Isabelle Villemure

Journal of Orthopaedic Research. 2011;29(4):473–480.

37 citations · 2 en 2025–2026

Calcium regulates cyclic compression-induced early changes in chondrocytes during in vitro cartilage tissue formation

Igal Raizman; J.N. Amritha De Croos; Robert Pilliar; Rita A. Kandel

Cell Calcium. 2010;48(4):232–242.

44 citations · 2 en 2025–2026

Matrix accumulation by articular chondrocytes during mechanical stimulation is influenced by integrin‐mediated cell spreading

Caroline Spiteri; Igal Raizman; Robert M. Pilliar; Rita A. Kandel

Journal of Biomedical Materials Research Part A. 2010.

19 citations · 2 en 2025–2026

Improved bioengineered cartilage tissue formation following cyclic compression is dependent on upregulation of MT1‐MMP

J. N. Amrith De Croos; Peter J. Roughley; Rita A. Kandel

Journal of Orthopaedic Research. 2010;28(7):921-927. DOI:10.1002/jor.21064. First online 2010-01-07. Methods provenance:earlier ORS2009poster1051;distinctive MT1MMPsiRNA/MMP13 result correspondence. Not official reprint;final journal methods not independently read.

7 citations · 1 en 2025–2026

In Vitro Comparison of the Mechanobiological Response of Porcine Growth Plate Explants under Static and Dynamic Loading [English translation]

Kim Sergerie

Thesis, École Polytechnique de Montréal, 2010. Original French title: Comparaison in vitro de la réponse mécanobiologique d'explants de plaques de croissance porcines sous chargements statique et dynamique.

Articular cartilage subpopulations respond differently to cyclic compression in vitro

Igal Raizman; J.N. Amritha De Croos; Jean-Philippe St-Pierre; Robert M. Pilliar; Rita A. Kandel

Tissue Engineering Part A. 2009;15(12):3789–3798.

12 citations · 1 en 2025–2026

Calcium Regulates Cyclic Compression-Induced Early Changes In Chondrocytes During In Vitro Tissue Formation

Igal Raizman

Master of Science thesis, University of Toronto, 2009.

Characterization of a Biodegradable Electrospun Polyurethane Nanofiber Scaffold Suitable for Annulus Fibrosus Tissue Engineering

Masoud Yeganegi

University of Toronto. Master of Applied Science and Engineering thesis. 2009.

0 citations · 0 en 2025–2026

Mechanical Forces Regulate Cartilage Tissue Formation by Chondrocytes Via Integrin-mediated Cell Spreading

Caroline Ferguson

Thesis, University of Toronto, 2009.

0 citations · 0 en 2025–2026

Multi-axial mechanical stimulation of tissue engineered cartilage: Review

Department of Mechanical and Materials Engineering, Department of Chemical Engineering, Queen's University, Kingston, Ontario, Canada; SD Waldman; DC Couto; MD Grynpas; RM Pilliar; RA Kandel

European Cells and Materials. 2007.

84 citations · 4 en 2025–2026

Membrane type-1 matrix metalloproteinase is induced following cyclic compression of in vitro grown bovine chondrocytes

J.N.A. De Croos; B. Jang; S.S. Dhaliwal; M.D. Grynpas; R.M. Pilliar; R.A. Kandel

Osteoarthritis and Cartilage. 2007;15(11):1301-1310.

20 citations · 0 en 2025–2026

Articular cartilage degradation and repair: mechanical components of matrix degradation and mechanisms of mesenchymal stem cell migration in tissue engineering [English translation]

Marc Thibault

École Polytechnique de Montréal. Ph.D. thesis, November 2006. Display title is an English translation of the original French title.

Dynamic shear stimulation of bovine cartilage biosynthesis of proteoglycan 4

Gayle E. Nugent; Nicole M. Aneloski; Tannin A. Schmidt; Barbara L. Schumacher; Michael S. Voegtline; Robert L. Sah

Arthritis & Rheumatism. 2006.

117 citations · 3 en 2025–2026

A single application of cyclic loading can accelerate matrix deposition and enhance the properties of tissue-engineered cartilage

S.D. Waldman; D.C. Couto; M.D. Grynpas; R.M. Pilliar; R.A. Kandel

Osteoarthritis and Cartilage. 2006;14(4):323–330.

110 citations · 6 en 2025–2026

Long‐term intermittent shear deformation improves the quality of cartilaginous tissue formed in vitro

Stephen D. Waldman; Caroline G. Spiteri; Marc D. Grynpas; Robert M. Pilliar; Rita A. Kandel

Journal of Orthopaedic Research. 2003.

199 citations · 5 en 2025–2026

Biomechanical regulation of articular cartilage metabolism of proteoglycan 4 and articular surface integrity

Gayle E. Nugent

University of California San Diego. PhD, Bioengineering. 2006

1 citation · 0 en 2025–2026

Long-Term Intermittent Compressive Stimulation Improves the Composition and Mechanical Properties of Tissue-Engineered Cartilage

Stephen D. Waldman; Caroline G. Spiteri; Marc D. Grynpas; Robert M. Pilliar; Rita A. Kandel

Tissue Engineering. 2004.

179 citations · 4 en 2025–2026

Cyclic compression of cartilage/bone explants in vitro leads to physical weakening, mechanical breakdown of collagen and release of matrix fragments

Marc Thibault; A. Robin Poole; Michael D. Buschmann

Journal of Orthopaedic Research. 2002;20(6):1265–1273.

137 citations · 6 en 2025–2026

Modulation of type II collagen synthesis in cartilage by mechanical compression [English translation]

Nicolas Tran-Khanh

École Polytechnique de Montréal / Université de Montréal. Master of Applied Science thesis, October 2000. Display title is an English translation; original abstract is in French.