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Retrouvez les travaux scientifiques utilisant les systèmes Biomomentum et explorez leurs applications.

Nikhil G. Menon

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3 juillet 2026 · Articles scientifiques

GBT-1118 Rescued Impaired Bone Formation but Failed to Rescue Material Properties in Humanized Sickle-Cell-Disease Murine Model

Kai Clarke; Wei He; Nikhil Menon; Tannin Schmidt; Alix Deymier; Marja Hurley

Cells. 2026;15(13):1209.

0 citations · 0 en 2025–2026

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19 juin 2025 · Articles scientifiques

Proteoglycan-4 (PRG4) serum concentration is lower in aged mice, and genetic deficiency impacts survival probability, blood parameters, and bone during aging

Adam P. Tanguay; Nikhil G. Menon; Emma Slavin; Mikayla Moody; Erin McEwen; Gregory D. Jay; Joseph Lorenzo; Jenna M. Bartley; Vanessa M. Scanlon; Alix C. Deymier; Tannin A. Schmidt

GeroScience (2025), Published: 19 June 2025

0 citations · 0 en 2025–2026

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18 décembre 2023 · Articles scientifiques

PRG4 deficiency in mice alters skeletal structure, mechanics, and calvarial osteoclastogenesis, and rhPRG4 inhibits in vitro osteoclastogenesis

Adam P. Tanguay; Nikhil G. Menon; Margaret H. Boudreau; Sandra Jastrzebski; Paige S. Woods; Erica A. Doyle; W. Brent Edwards; Gregory D. Jay; Alix C. Deymier; Joseph Lorenzo; Sun‐Kyeong Lee; Tannin A. Schmidt

Journal of Orthopaedic Research. 2024;42(6):1231–1243. First published online 18 December 2023.

3 citations · 3 en 2025–2026

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Publications

Nikhil G. Menon

GBT-1118 Rescued Impaired Bone Formation but Failed to Rescue Material Properties in Humanized Sickle-Cell-Disease Murine Model

Proteoglycan-4 (PRG4) serum concentration is lower in aged mice, and genetic deficiency impacts survival probability, blood parameters, and bone during aging

PRG4 deficiency in mice alters skeletal structure, mechanics, and calvarial osteoclastogenesis, and rhPRG4 inhibits in vitro osteoclastogenesis

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