On the fractional transversely isotropic functionally graded nature of soft biological tissues: Application to the meniscal tissue

Abstract

This paper focuses on the origin of the poroelastic anisotropic behaviour of the meniscal tissue and its spatially varying properties. We present confined compression creep test results on samples extracted from three parts of the tissue (Central body, Anterior horn and Posterior horn) in three orientations (Circumferential, Radial and Vertical). We show that a poroelastic model in which the fluid flow evolution is ruled by non-integer order operators (fractional Darcy’s law) provides accurate agreement with the experimental creep data. The model is validated against two additional sets of experimental data: stress relaxation and fluid loss during the consolidation process measured as weight reduction. Results show that the meniscus can be considered as a transversely isotropic poroelastic material. This behaviour is due to the fluid flow rate being about three times higher in the circumferential direction than in the radial and vertical directions in the body region of the meniscus. The 3D fractional poroelastic model is implemented in the finite element software to estimate the weight loss during the confined compression tests.

Keywords

Meniscus; Fractional poroelasticity; Confined compression tests; Anomalous diffusion; Finite element simulation