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Pro‐inflammatory immunity supports fibrosis advancement in epidermolysis bullosa: intervention with Ang‐(1‐7)

  • par garon@biomomentum.com

Rocco Bernasconi; Kerstin Thriene; Elena Romero‐Fernández; Christine Gretzmeier; Tobias Kühl; Mareike Maler; Pauline Nauroy; Svenja Kleiser; Anne‐Catherine Rühl‐Muth; Michael Stumpe; Dimitra Kiritsi; Stefan F Martin; Boris Hinz; Leena Bruckner‐Tuderman; Jörn Dengjel; Alexander Nyström
EMBO Molecular Medicine. 2021;13(10):e14392.

https://doi.org/10.15252/emmm.202114392

45 citations · 16 en 2025–2026

Les titres, résumés et légendes des publications sont présentés en anglais.

Editorial summary

Inflammatory mechanisms contributing to fibrosis were studied in recessive dystrophic epidermolysis bullosa. Cellular and animal analyses evaluated progression and the effects of angiotensin-(1–7). Mechanical tissue measurements complement evidence linking inflammatory responses with structural deterioration and treatment-related changes in the mouse model.

Utilisation des équipements

Mesures de rigidité par indentation au Mach-1 de peau de patte de souris témoins et atteintes d’épidermolyse bulleuse.

Matériaux (1)

Configurations de test (1)

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