Injectable Lyophilized Chitosan-Thrombin-Platelet-Rich Plasma (CS-FIIa-PRP) Implant to Promote Tissue Regeneration: In Vitro and Ex Vivo Solidification Properties

Editorial summary

Freeze-dried chitosan formulations reconstituted in platelet-rich plasma were studied as injectable repair materials. The effects of thrombin on solidification, handling and tissue adherence were assessed in vitro and ex vivo. The work investigates the balance between useful working time and subsequent biomaterial stabilization.