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Heparin-Modified Collagen Gels for Controlled Release of Pleiotrophin: Potential for Vascular Applications

  • par garon@biomomentum.com

Francesco Copes; Pascale Chevallier; Caroline Loy; Daniele Pezzoli; Francesca Boccafoschi; Diego Mantovani
Frontiers in Bioengineering and Biotechnology. 2019;7:74.

https://doi.org/10.3389/fbioe.2019.00074

32 citations · 6 en 2025–2026

Les titres, résumés et légendes des publications sont présentés en anglais.

Editorial summary

Collagen gels modified with heparin were investigated for delivery of pleiotrophin in vascular applications. Release behavior, endothelial and smooth-muscle cell responses, and blood compatibility were evaluated. The work examines a material strategy intended to support endothelial recovery while limiting unfavorable cellular responses.

Utilisation des équipements

Essais de compression non confinée et de relaxation de gels de collagène modifiés à l’héparine avec le Mach-1.

Matériaux (1)

Configurations de test (2)

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