Estimation and sensitivity to cartilage degradation of electromechanical coupling coefficients derived using spatially resolved streaming potentials

Abstract — Editorial summary

This conference study examined an electromechanical coupling coefficient calculated from spatially integrated cartilage electrical potentials and measured force. Experiments varied saline concentration and compared trypsin-treated tissue with controls. The coefficient depended on ionic conditions and decreased substantially after enzymatic degradation. It was relatively stable during the release phase of loading, while compression-phase values were less constant. The results suggest that combining electrical and force measurements can provide information about cartilage deterioration and help separate tissue effects from some geometric influences.

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