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Dose‐Dependent, Biomechanical Recovery of Permeability Ex Vivo in GAG‐Depleted Cartilage With a Synthetic Polyelectrolyte, Polystyrene Sulfonate

  • par garon@biomomentum.com

Qurat‐Ul‐Ain Bhatti; Shalini Sundar; Allison Koopman; Zoe A. Fields; Kyla F. Ortved; David L. Burris; Justin Parreno; Laure V. Kayser; Charles B. Dhong
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2026.

https://doi.org/10.1002/jor.70177

1 citation · 1 en 2025–2026

Les titres, résumés et légendes des publications sont présentés en anglais.

Editorial summary

Cartilage depleted of glycosaminoglycans was treated with polystyrene sulfonate to investigate recovery of biomechanical function. The study examines dose-dependent changes in tissue properties and transport behavior. Creep measurements provide material parameters for comparison between healthy, depleted and treated explants.

Utilisation des équipements

Le Mach-1 impose une charge d’indentation constante aux explants de cartilage pour l’analyse du fluage biphasique et l’estimation de la perméabilité.

Matériaux (1)

Configurations de test (1)

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