Conception et validation d’une sonde arthroscopique pour l’évaluation des propriétés électromécaniques fonctionnelles du cartilage articulaire

Abstract — Editorial summary

This doctoral thesis presents the design and validation of an arthroscopic probe that measures cartilage streaming potentials using thirty-seven microelectrodes. Development work included electrical safety and preparation for clinical evaluation. Measurements on excised equine and human cartilage were compared with mechanical and biochemical properties. A multiuser study on a human knee showed good agreement between operators, with an intraclass correlation of 0.87. Modelling also examined the effects of cartilage thickness, fibril stiffness and electrical behaviour outside the contact region. Together, these investigations support interpretation of the probe’s response as an indicator of cartilage function.

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