Assessment of human tali articular cartilage

Christoph Becher; Caroline Kröger; Benjamin Fleischer; Christof Hurschler
Orthopädische und Unfallchirurgische Praxis. 2016;5(12):702–706. Original German title: Evaluation der Knorpelqualität am Talus. Printed DOI ; resolution not confirmed.

https://doi.org/10.3238/oup.2016.0702%E2%80%930706

Les titres, résumés et légendes des publications sont présentés en anglais.

Summary

The non-invasive objective intraoperative classification of the cartilage could offer a new option for decision-making with respect to treatment of articular cartilage defects. In this in-vitro study, 10 human tali were evaluated with an indentation probe to measure the results of compression-induced streaming potentials (SPI – Arthro BST, Biomomentum Inc., Laval, Canada) and near-infrared spectroscopy (NIRS – arthrospec GmbH, Jena, Germany). The degradation level of the tissue was determined macroscopically with the ICRS-Score and histologically in extracted 36 cartilage cylinders by using the Mankin-Score.

The measurements could be performed with statistically significant (p < 0,001) interobserver agreement with a computed ICC of 0,87 (0,77–0,93) for SPI values and 0,76 (0,63–0,85) for the NIRS values among 3 users. However, no significant correlations were found between the score results (ICRS and Mankin) and the SPI and NIRS values, respectively. Thus, since reference data is not available at this point, no valid statements on the cartilage quality and classification at the talus can be made with either of the 2 techniques.

Keywords: near infrared spectroscopy (NIRS), streaming
potential integrals (SPI), articular cartilage, osteoarthritis,
ICRS/Mankin score

Utilisation des équipements

L’Arthro-BST mesurait les potentiels d’écoulement induits par compression à des sites définis du cartilage de talus humains. Ces mesures étaient comparées à la spectroscopie proche infrarouge et aux scores de qualité du cartilage, obtenus séparément.