Assessing the Impact of Partial Decellularization on Tracheal Chondrocytes and Extracellular Matrix in Airway Reconstruction

Editorial summary

Partial decellularization of tracheal grafts was examined using mouse and rabbit models. The study compares preservation of cells and extracellular matrix with subsequent graft behavior. Scaling the approach to larger tissues exposed differences that were not apparent from preimplantation measurements alone.