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Aberrant Chitinase 3‐Like 1 Expression in Basal Cells Contributes to Systemic Sclerosis Fibrosis

  • par garon@biomomentum.com

Xiuyuan Wang; Tianbao Ye; Junxia Huang; Feifei Hu; Chengjie Huang; Bei Gu; Xinzhi Xu; Ji Yang
Advanced Science. 2025;12(6):e2310169.

https://doi.org/10.1002/advs.202310169

7 citations · 7 en 2025–2026

Les titres, résumés et légendes des publications sont présentés en anglais.

Editorial summary

The role of chitinase 3-like 1 in systemic-sclerosis fibrosis was investigated through cellular and animal experiments. The study connects expression in basal cells with inflammatory signaling and fibrotic outcomes. Mechanical skin assessment complements the molecular and tissue analyses of the proposed pathway.

Utilisation des équipements

Essais de traction et de rupture au Mach-1 sur de la peau dorsale prélevée chez la souris.

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