A transport model of electrolyte convection through a charged membrane predicts generation of net charge at membrane/electrolyte interfaces

Abstract — Editorial summary

Electrical measurements during cartilage compression had revealed positive potentials in the surrounding saline bath as well as negative potentials within the tissue. This theoretical study investigated whether fluid-driven ion transport near a charged interface could explain that observation. A membrane transport model examined how forced electrolyte convection changes mobile-ion concentrations and electrical potentials across a charged membrane. The approach links interfacial charge generation to the movement of ions through a spatially varying electrical environment. Its purpose is to explain an electromechanical mechanism, rather than to report a clinical test of cartilage degeneration.

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