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A 3D Bioprinted Cortical Organoid Platform for Modeling Human Brain Development

  • by garon@biomomentum.com

Melissa A. Cadena; Anson Sing; Kylie Taylor; Linqi Jin; Liqun Ning; Mehdi Salar Amoli; Yamini Singh; Samantha N. Lanjewar; Martin L. Tomov; Vahid Serpooshan; Steven A. Sloan
Advanced Healthcare Materials. 2024;13(27):e2401603.

https://doi.org/10.1002/adhm.202401603

40 citations · 36 in 2025–2026

Editorial summary

A bioprinted platform was developed for culturing cortical organoids in a controlled three-dimensional environment. Gelatin-based bioinks and channel structures were evaluated for mechanical suitability, cell viability and interactions with endothelial cells. The platform supports investigation of more complex vascularized models of brain development.

Equipment used

Mach-1 microindentation used to characterize the elastic properties of photocrosslinked GelMA bioink discs.

Materials (1)

Test configurations (1)

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