Watch: Toothpaste testing in a brushing simulatorTissue testing · 0:12
Toothpaste testing in a brushing simulator
A demonstration of toothpaste testing in a tooth brushing simulator.
Test configurations
Mechanical Stimulation (Shear)
The shear stimulation of mechanically-responsive cell constructs has been demonstrated to have important effects on the cell's activity, in particular, over the production of extracellular matrix components. This mechanical stimulation is normally performed during cell culture. Biomomentum's mechanical tester can be installed in a standard incubator in dry mode condition. Closed testing chambers have been designed for this particular application. Humidity and gas level are controlled directly inside the chamber made of material compatible with cell culture.
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Toothpaste testing
FAQ
How does the "Sinusoid" model works?
This feature is used to obtain the Frequency, Amplitude and Offset of a sinusoidal signal. A blue line displays the theoretical sinusoid with the Frequency, Amplitude and Offset obtained (Figure 1). The values of the Frequency, Amplitude and Offset are indicated in the "Results" field. The units vary according to the graph’s axes.
This feature can also be used for sinusoidal stimulus-response analysis. Sinusoidal stimulus shall be selected on the x-axis and the sinusoidal response on the y-axis. The Modulus is the ratio of the response Amplitude over the stimulus Amplitude. The Phase is the phase difference between the response and the stimulus. The Modulus’ is computed as the Modulus*Cos(Phase) and the Modulus” is computed as the Modulus*Sin(Phase). A blue line displays the theoretical sinusoidal stimulus-response with the Frequency, Modulus and Phase obtained (Figure 2). The values of the Modulus and Phase are indicated in the “Results” field. The units vary according to the graph’s axes.
One use for this feature would be to compute material properties by multiplying the Modulus obtained by the appropriate geometric factors. For example, the Young’s Modulus can be obtained during uniaxial compression or tension on cylindrical sample with t/pi*r2 as the geometric factor, t is the thickness and r is the radius of the sample.
Mach-1 Analysis – Sinusoid – Example for stimulus-response analysis